An estimated 22,000 new cases of ovarian cancer are diagnosed in the United States each year, and mortality rates are high if the disease is not caught and treated early.
Members of the clinical community have attempted to identify modifiable risk factors. Some data suggested an association between genital talcum powder use and ovarian cancer risk. However, these data have not been consistent. If you are looking for the talcum powder lawsuit center, then you can visit http://www.talcumpowdercancerlawsuitcenter.com/talcum-powder-cancer-risk.asp.
For this reason, Paolo Boffetta, MD, MPH, professor of medicine at Mount Sinai School of Medicine and director of cancer prevention at the Tisch Cancer Institute at Mount Sinai, and colleagues conducted a review and meta-analysis of systemic of 27 studies that evaluated the association between use of talc genital and ovarian cancer risk.
Results showed genital ever use talc associated with a summary relative risk of 1.22 (95% CI, 1.13 to 1.3). When the researchers stratified the analysis according to the design of the study, they looked at the relationship between the risk of ovarian cancer and genital never use talcum powder in case-control studies (RR = 1.26; 95% CI, 1.17 to 1.35), but not in the study cohort (RR = 1.02; 95% CI, 0.85 to 1.2).
"Some studies have shown a relationship between the powder use and ovarian cancer, the combined evidence falls short of showing a causal link," Boffetta said in a press release. "It is too early to conclude that the powder use causes ovarian cancer."
HemOnc Today spoke with Boffetta about the findings, their potential implications, and questions that subsequent research will try to address.